Human SLC25A12 protein (Recombinant) (N-His) (STJP010747)

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STJP010747
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Short Description :Recombinant-Human SLC25A12-N-His protein was developed from e.coli for the region N-His. For use in research applications.
Applications:ELISA/Immunogen/SDS-PAGE/WB
Host:E.coli
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Dilution Range:Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Formulation:Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction:Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol:SLC25A12
Gene ID:8604
Uniprot ID:S2512_HUMAN
Immunogen:Homo sapiens (Human)
Immunogen Region:Gly11-Gln311
Function Mitochondrial electrogenic aspartate/glutamate antiporter that favors efflux of aspartate and entry of glutamate and proton within the mitochondria as part of the malate-aspartate shuttle. Also mediates the uptake of L-cysteinesulfinate (3-sulfino-L-alanine) by mitochondria in exchange of L-glutamate and proton. Can also exchange L-cysteinesulfinate with aspartate in their anionic form without any proton translocation. Lacks transport activity towards L-glutamine or gamma-aminobutyric acid (GABA).
Protein Name Electrogenic Aspartate/Glutamate Antiporter Slc25a12 - Mitochondrial
Araceli Hiperlarga
Aralar
Aralar1
Mitochondrial Aspartate Glutamate Carrier 1
Solute Carrier Family 25 Member 12
Database Links Reactome: R-HSA-1268020
Reactome: R-HSA-8963693
Reactome: R-HSA-9856872
Cellular Localisation Mitochondrion Inner Membrane
Multi-Pass Membrane Protein
Alternative Protein Names Electrogenic Aspartate/Glutamate Antiporter Slc25a12 - Mitochondrial protein
Araceli Hiperlarga protein
Aralar protein
Aralar1 protein
Mitochondrial Aspartate Glutamate Carrier 1 protein
Solute Carrier Family 25 Member 12 protein
SLC25A12 protein
AGC1 protein
ARALAR1 protein

Information sourced from Uniprot.org