Human SLC1A6 protein (Recombinant) (N-GST & C-His) (STJP015809)

SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
STJP015809
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General Information

Short DescriptionRecombinant-Human SLC1A6-N-GST & C-His protein was developed from e.coli for the region N-GST & C-His. For use in research applications.
ApplicationsELISA/Immunogen/SDS-PAGE/WB
HostE.coli
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

Dilution RangeReconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
FormulationLyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol.
Storage InstructionUse a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
EndotoxinPlease contact us for further information.

Target Information

Gene SymbolSLC1A6
Gene ID6511
Uniprot IDEAA4_HUMAN
ImmunogenHomo sapiens (Human)
Immunogen RegionIle153-Ser262

Additional Info

Function Sodium-dependent, high-affinity amino acid transporter that mediates the uptake of L-glutamate and also L-aspartate and D-aspartate. Functions as a symporter that transports one amino acid molecule together with two or three Na(+) ions and one proton, in parallel with the counter-transport of one K(+) ion. Mediates Cl(-) flux that is not coupled to amino acid transport.this avoids the accumulation of negative charges due to aspartate and Na(+) symport. Plays a redundant role in the rapid removal of released glutamate from the synaptic cleft, which is essential for terminating the postsynaptic action of glutamate (Probable).
Protein Name Excitatory Amino Acid Transporter 4
Sodium-Dependent Glutamate/Aspartate Transporter
Solute Carrier Family 1 Member 6
Database Links Reactome: R-HSA-210500
Reactome: R-HSA-425393
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Alternative Protein Names Excitatory Amino Acid Transporter 4 protein
Sodium-Dependent Glutamate/Aspartate Transporter protein
Solute Carrier Family 1 Member 6 protein
SLC1A6 protein
EAAT4 protein

Information sourced from Uniprot.org

Citations

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