Human SLC13A2 protein (Recombinant) (N-GST & C-His) (STJP016101)
SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human SLC13A2-N-GST & C-His protein was developed from e.coli for the region N-GST & C-His. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
| Endotoxin | Please contact us for further information. |
Target Information
| Gene Symbol | SLC13A2 |
| Gene ID | 9058 |
| Uniprot ID | S13A2_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Phe289-Ala331&Pro385-Lys447 |
Additional Info
| Function | Low-affinity sodium-dicarboxylate cotransporter, that mediates the entry of citric acid cycle intermediates, such as succinate, citrate, fumarate and alpha-ketoglutarate (2-oxoglutarate) into the small intestine and renal proximal tubule. Transports the dicarboxylate into the cell with a probable stoichiometry of 3 Na(+) for 1 divalent dicarboxylate, rendering the process electrogenic. Citrate is transported in protonated form as a divalent anion, rather than the trivalent form which is normally found in blood. Has a critical role in renal dicarboxylate transport. |
| Protein Name | Solute Carrier Family 13 Member 2Na(+/Dicarboxylate Cotransporter 1Nadc-1Renal Sodium/Dicarboxylate Cotransporter |
| Database Links | Reactome: R-HSA-433137 |
| Cellular Localisation | Apical Cell MembraneMulti-Pass Membrane Protein |
| Alternative Protein Names | Solute Carrier Family 13 Member 2 proteinNa(+/Dicarboxylate Cotransporter 1 proteinNadc-1 proteinRenal Sodium/Dicarboxylate Cotransporter proteinSLC13A2 proteinNADC1 proteinSDCT1 protein |
Information sourced from Uniprot.org