Human SLC12A2 protein (Recombinant) (N-His) (STJP010915)
SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human SLC12A2-N-His protein was developed from e.coli for the region N-His. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
Target Information
| Gene Symbol | SLC12A2 |
| Gene ID | 6558 |
| Uniprot ID | S12A2_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Asn1002-Ser1212 |
Additional Info
| Post Translational Modifications | Phosphorylated at Thr-203, Thr-207 and Thr-212 by OXSR1/OSR1 and STK39/SPAK downstream of WNK kinases (WNK1, WNK2, WNK3 or WNK4), promoting its activity. |
| Function | Cation-chloride cotransporter which mediates the electroneutral transport of chloride, potassium and/or sodium ions across the membrane. Plays a vital role in the regulation of ionic balance and cell volume. |
| Protein Name | Solute Carrier Family 12 Member 2Basolateral Na-K-Cl SymporterBumetanide-Sensitive Sodium-(Potassium-Chloride Cotransporter 2Bsc2Na-K-2cl Cotransporter 1Hnkcc1 |
| Database Links | Reactome: R-HSA-426117 |
| Cellular Localisation | Basolateral Cell MembraneMulti-Pass Membrane Protein |
| Alternative Protein Names | Solute Carrier Family 12 Member 2 proteinBasolateral Na-K-Cl Symporter proteinBumetanide-Sensitive Sodium-(Potassium-Chloride Cotransporter 2 proteinBsc2 proteinNa-K-2cl Cotransporter 1 proteinHnkcc1 proteinSLC12A2 proteinNKCC1 protein |
Information sourced from Uniprot.org