• Human SIRP gamma/CD172g protein (Recombinant) (C-His-Avi) {Biotin} (STJP001686)

Human SIRP gamma/CD172g protein (Recombinant) (C-His-Avi) {Biotin} (STJP001686)

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STJP001686

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Host: HEK293
Note: STRICTLY FOR FURTHER RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Recombinant-Human SIRP gamma/CD172g-C-His-Avi protein was developed from hek293 and has a target region of C-His-Avi. For use in research applications.
Conjugation: Biotin
Formulation: Lyophilised from 0.2 µm filtered PBS solution pH7.4.
Dilution Range: Upon receipt centrifuge vial to ensure maximal product extraction, recommended: 20sec, 5K RPM
Storage Instruction: The lyophilized protein is stable for at least 1 year from date of receipt at-20°C.
Endotoxin: Endotoxin content was assayed using a LAL gel clot method. Endotoxin level was found to be less than 0.1 ng/µg (1EU/µg).
Gene Symbol: SIRPG
Gene ID: 55423
Uniprot ID: SIRPG_HUMAN
Immunogen Region: Glu29-Pro360
Immunogen: DNA sequence encoding Human SIRP gamma/CD172g including a C-His-Avi tag was expressed in HEK293 Cells. The recombinant protein was then biotinylated site specific using the AVItag biotinylation technology.
Function Probable immunoglobulin-like cell surface receptor. On binding with CD47, mediates cell-cell adhesion. Engagement on T-cells by CD47 on antigen-presenting cells results in enhanced antigen-specific T-cell proliferation and costimulates T-cell activation.
Protein Name Signal-Regulatory Protein Gamma
Sirp-Gamma
Cd172 Antigen-Like Family Member B
Signal-Regulatory Protein Beta-2
Sirp-B2
Sirp-Beta-2
Cd Antigen Cd172g
Database Links Reactome: R-HSA-202733
Reactome: R-HSA-391160
Cellular Localisation Membrane
Single-Pass Type I Membrane Protein
Alternative Protein Names Signal-Regulatory Protein Gamma protein
Sirp-Gamma protein
Cd172 Antigen-Like Family Member B protein
Signal-Regulatory Protein Beta-2 protein
Sirp-B2 protein
Sirp-Beta-2 protein
Cd Antigen Cd172g protein
SIRPG protein
SIRPB2 protein

Information sourced from Uniprot.org

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