Human SESN3 (Sestrin 3) Sandwich ELISA Kit (STJE0012113)
SPECIFICATIONS
General Information
| Short Description | This SESN3 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human tissue homogenates or other biological fluids.. |
| Applications | ELISA |
| Reactivity | Human |
| Sensitivity | 0.056ng/mL |
| Detection Limit | 0.156-10ng/mL |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Storage Instruction | Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time | 4.5 hrs |
Target Information
| Gene Symbol | SESN3 |
| Gene ID | 143686 |
| Uniprot ID | SESN3_HUMAN |
| Sample Type | tissue homogenates or other biological fluids. |
Additional Info
| Tissue Specificity | Widely expressed. |
| Post Translational Modifications | |
| Function | May function as an intracellular leucine sensor that negatively regulates the TORC1 signaling pathway. May also regulate the insulin-receptor signaling pathway through activation of TORC2. This metabolic regulator may also play a role in protection against oxidative and genotoxic stresses. May prevent the accumulation of reactive oxygen species (ROS) through the alkylhydroperoxide reductase activity born by the N-terminal domain of the protein. |
| Protein Name | Sestrin-3 |
| Database Links | Reactome: R-HSA-5628897 |
| Cellular Localisation | Cytoplasm |
| Alternative ELISA Names | Sestrin-3 ELISA kitSESN3 ELISA kitSEST3 ELISA kit |
| output |
Information sourced from Uniprot.org