Human SerpinB3/SCCA (SerpinB3/SCCA) Antibody Pair (STJAP00914)
General Information
| Short Description | This SerpinB3/SCCA antibody pair contains complimentary capture and detection antibodies, which work together under the principals of the. |
| Applications | ELISA |
| Host | Rabbit/Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal/Monoclonal |
| Clone ID | R06-8Z-2/R08-5K-1 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | Affinity Purification |
| Dilution Range | Determined by end user |
| Formulation | 0.01M PBS, pH 7.2 |
| Storage Instruction | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
Target Information
| Gene Symbol | SERPINB3 |
| Gene ID | 6317 |
| Uniprot ID | SPB3_HUMAN |
| Immunogen | Recombinant protein |
Additional Info
| Tissue Specificity | Squamous cells. Expressed in some hepatocellular carcinoma (at protein level). |
| Function | May act as a papain-like cysteine protease inhibitor to modulate the host immune response against tumor cells. Also functions as an inhibitor of UV-induced apoptosis via suppression of the activity of c-Jun NH(2)-terminal kinase (JNK1). |
| Protein Name | Serpin B3Protein T4-ASquamous Cell Carcinoma Antigen 1Scca-1 |
| Database Links | Reactome: R-HSA-6798695 |
| Cellular Localisation | CytoplasmSeems To Also Be Secreted In Plasma By Cancerous Cells But At A Low Level |
| Alternative Antibody Pair Names | Serpin B3 antibody pairProtein T4-A antibody pairSquamous Cell Carcinoma Antigen 1 antibody pairScca-1 antibody pairSERPINB3 antibody pairSCCA antibody pairSCCA1 antibody pair |
Information sourced from Uniprot.org
Citations
Product Review
Frequently Asked Questions
Common questions about Human SerpinB3/SCCA (SerpinB3/SCCA) Antibody Pair (STJAP00914)
This antibody pair is designed to detect human SerpinB3/SCCA (UniProt P29508) and has confirmed reactivity with human samples only.
Both antibodies are rabbit monoclonal IgGs (clone IDs R06-8Z-2 and R08-5K-1), supplied unconjugated and affinity purified, formulated in 0.01M PBS at pH 7.2.
This antibody pair has been validated for use in ELISA. No other assay formats are listed as validated applications.
Working concentrations are not pre-defined for this product and must be determined by the end user through titration optimization within their specific assay conditions.
Both antibodies should be stored at 4°C for short-term use. For long-term storage, aliquot and store at -20°C. Repeated freeze/thaw cycles should be avoided to maintain activity.
Orders typically arrive within 1 to 2 weeks, and often sooner depending on your location. If your timeline is critical, please contact us before ordering and we can advise on current lead times.
This product is shipped on gel ice packs to maintain integrity during transit. Priority shipping is used as standard to minimise time in transit.
A Certificate of Analysis (CoA) is provided with every order. If you do not receive one, please contact us and we will issue it promptly.