Human Serpin B2/PAI-2 protein (Recombinant) (His-Tag) (STJP019504)
SPECIFICATIONS
HostE.coli
ImmunogenHuman
General Information
| Short Description | Recombinant-Human Serpin B2/PAI-2-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Applications | SDS-PAGE |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Concentration | 0.5 mg/mL |
| Formulation | Liquid in phosphate-Buffered Saline (pH 7.4) containing 30% Glycerol, 1mM DTT |
| Storage Instruction | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | SERPINB2 |
| Gene ID | 5055 |
| Uniprot ID | PAI2_HUMAN |
| Accession Number | NP_001137290 |
| Immunogen | Human |
| Immunogen Region | 1-415aa |
| Immunogen Sequence |
Additional Info
| Post Translational Modifications | The signal sequence is not cleaved. |
| Function | Inhibits urokinase-type plasminogen activator. The monocyte derived PAI-2 is distinct from the endothelial cell-derived PAI-1. |
| Protein Name | Plasminogen Activator Inhibitor 2Pai-2Monocyte Arg-SerpinPlacental Plasminogen Activator InhibitorSerpin B2Urokinase Inhibitor |
| Database Links | Reactome: R-HSA-75205Reactome: R-HSA-8950505 |
| Cellular Localisation | CytoplasmSecretedExtracellular Space |
| Alternative Protein Names | Plasminogen Activator Inhibitor 2 proteinPai-2 proteinMonocyte Arg-Serpin proteinPlacental Plasminogen Activator Inhibitor proteinSerpin B2 proteinUrokinase Inhibitor proteinSERPINB2 proteinPAI2 proteinPLANH2 protein |
Information sourced from Uniprot.org