Tissue Specificity | Widely expressed. Expressed in lymph node. |
Post Translational Modifications | |
Function | Filament-forming cytoskeletal GTPase. Involved in spermatogenesis. Involved in the morphogenesis of sperm heads and the elongation of sperm tails probably implicating the association with alpha- and beta-tubulins. Forms a filamentous structure with SEPTIN7, SEPTIN6, SEPTIN2 and probably SEPTIN4 at the sperm annulus which is required for the structural integrity and motility of the sperm tail during postmeiotic differentiation. May play a role in cytokinesis (Potential). |
Protein Name | Septin-12 |
Database Links | |
Cellular Localisation | CytoplasmCytoskeletonSpindleNucleusCell ProjectionCiliumFlagellumAt InterphaseForms A Filamentous Structure In The CytoplasmDuring AnaphaseTranslocates To The Central Spindle Region And To The Midbody During CytokinesisFound In The Sperm AnnulusColocalized With Spag4 At The Nuclear Periphery In Round SpermatidsAt Sperm Neck In Elongated Spermatids And At Midpiece Regions In Ejaculated Spermatozoa |
Alternative ELISA Names | Septin-12 ELISA kitSEPTIN12 ELISA kitSEPT12 ELISA kit |
output | |
Information sourced from Uniprot.org