• Human SELL/L-selectin/LAM-1/CD62L protein (Recombinant) (C-hFc&His) (STJP001025)

Human SELL/L-selectin/LAM-1/CD62L protein (Recombinant) (C-hFc&His) (STJP001025)

SKU:
STJP001025

€111.88 - €280.63
Current Stock:
Host: HEK293 cells
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Formulation: Lyophilised from a 0.22 Mu m filtered solution of PBS, pH 7.4.
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Determination Method: < 0.1 EU/Mu g of the protein by LAL method.
Gene Symbol: SELL
Gene ID: 6402
Uniprot ID: LYAM1_HUMAN
Immunogen: Recombinant Human SELL/L-selectin/LAM-1/CD62L Protein is produced by HEK293 expression system. The target protein is expressed with sequence (Trp52-Asn345) of human L-Selectin/CD62L (Accession #NP_000646.2) fused with an Fc, 6×His tag at the C-termin
Immunogen Sequence: WTYHYSEKPMNWQRARRFCR DNYTDLVAIQNKAEIEYLEK TLPFSRSYYWIGIRKIGGIW TWVGTNKSLTEEAENWGDGE PNNKKNKEDCVEIYIKRNKD AGKWNDDACHKLKAALCYTA SCQPWSCSGHGECVEIINNY TCNCDVGYYGPQCQFVIQCE PLEAPELGTMDCTHPLGNFS FSSQCAFSCSEGTNLTGIEE TTCGPFGNWSSPEPTCQVIQ CEPLSAPDLGIMNCSHPLA
Post Translational Modifications N-glycosylated.
Function Calcium-dependent lectin that mediates cell adhesion by binding to glycoproteins on neighboring cells. Mediates the adherence of lymphocytes to endothelial cells of high endothelial venules in peripheral lymph nodes. Promotes initial tethering and rolling of leukocytes in endothelia.
Protein Name L-Selectin
Cd62 Antigen-Like Family Member L
Leukocyte Adhesion Molecule 1
Lam-1
Leukocyte Surface Antigen Leu-8
Leukocyte-Endothelial Cell Adhesion Molecule 1
Lecam1
Lymph Node Homing Receptor
Tq1
Gp90-Mel
Cd Antigen Cd62l
Database Links Reactome: R-HSA-198933
Reactome: R-HSA-202733
Reactome: R-HSA-6798695
Cellular Localisation Cell Membrane
Single-Pass Type I Membrane Protein
Alternative Protein Names L-Selectin protein
Cd62 Antigen-Like Family Member L protein
Leukocyte Adhesion Molecule 1 protein
Lam-1 protein
Leukocyte Surface Antigen Leu-8 protein
Leukocyte-Endothelial Cell Adhesion Molecule 1 protein
Lecam1 protein
Lymph Node Homing Receptor protein
Tq1 protein
Gp90-Mel protein
Cd Antigen Cd62l protein
SELL protein
LNHR protein
LYAM1 protein

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance