| Host: |
HEK293 |
| Note: |
STRICTLY FOR FURTHER RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Recombinant-Human L-Selectin (CD62L)-protein was developed from hek293. For use in research applications. |
| Conjugation: |
Unconjugated |
| Formulation: |
Lyophilised from 0.2 Mu m filtered PBS solution, pH7.2, 5% Trehalose. |
| Storage Instruction: |
Can be stored in working aliquots at 2°C-8°C C for one month, or at-20°C to-70°C for 1 year. Avoid repeated freeze/thaw cycles. NA |
| Endotoxin: |
Endotoxin content was assayed using a LAL gel clot method. Endotoxin level was found to be less than 0.1 ng/µg (1EU/µg). NA |
| Immunoreactivity: |
The activity was tested by the ability of immobilized recombinant human L-Selectin to bind Human CD34 NA |
| Gene Symbol: |
SELL |
| Gene ID: |
6402 |
| Uniprot ID: |
LYAM1_HUMAN |
| Immunogen Region: |
ECD |
| Immunogen: |
Optimized DNA sequence encoding extracellular domain of Human L-Selectin including a C-terminal His tag was expressed in HEK293 cells. NA |
| Tissue Specificity | Expressed in B-cell lines and T-lymphocytes. |
| Post Translational Modifications | N-glycosylated. |
| Function | Calcium-dependent lectin that mediates cell adhesion by binding to glycoproteins on neighboring cells. Mediates the adherence of lymphocytes to endothelial cells of high endothelial venules in peripheral lymph nodes. Promotes initial tethering and rolling of leukocytes in endothelia. |
| Protein Name | L-SelectinCd62 Antigen-Like Family Member LLeukocyte Adhesion Molecule 1Lam-1Leukocyte Surface Antigen Leu-8Leukocyte-Endothelial Cell Adhesion Molecule 1Lecam1Lymph Node Homing ReceptorTq1Gp90-MelCd Antigen Cd62l |
| Database Links | Reactome: R-HSA-198933Reactome: R-HSA-202733Reactome: R-HSA-6798695 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane Protein |
| Alternative Protein Names | L-Selectin proteinCd62 Antigen-Like Family Member L proteinLeukocyte Adhesion Molecule 1 proteinLam-1 proteinLeukocyte Surface Antigen Leu-8 proteinLeukocyte-Endothelial Cell Adhesion Molecule 1 proteinLecam1 proteinLymph Node Homing Receptor proteinTq1 proteinGp90-Mel proteinCd Antigen Cd62l proteinSELL proteinLNHR proteinLYAM1 protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
