Human SDHB (Succinate Dehydrogenase Complex Subunit B) Sandwich ELISA Kit Ready-To-Use Kit (STJE0018451)
SPECIFICATIONS
General Information
| Short Description | This SDHB Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human tissue homogenates or other biological fluids.. |
| Applications | ELISA |
| Reactivity | Human |
| Sensitivity | 0.067ng/mL |
| Detection Limit | 0.156-10ng/mL |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Storage Instruction | The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time | 3 hrs |
Target Information
| Gene Symbol | SDHB |
| Gene ID | 6390 |
| Uniprot ID | SDHB_HUMAN |
| Immunogen Region | Ready-To-Use |
| Sample Type | tissue homogenates or other biological fluids. |
Additional Info
| Tissue Specificity | |
| Post Translational Modifications | |
| Function | Iron-sulfur protein (IP) subunit of the succinate dehydrogenase complex (mitochondrial respiratory chain complex II), responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). SDH also oxidizes malate to the non-canonical enol form of oxaloacetate, enol-oxaloacetate. Enol-oxaloacetate, which is a potent inhibitor of the succinate dehydrogenase activity, is further isomerized into keto-oxaloacetate. |
| Protein Name | Succinate Dehydrogenase Ubiquinone Iron-Sulfur Subunit - MitochondrialIron-Sulfur Subunit Of Complex IiIpMalate Dehydrogenase Quinone Iron-Sulfur Subunit |
| Database Links | Reactome: R-HSA-611105Reactome: R-HSA-71403Reactome: R-HSA-9854311 |
| Cellular Localisation | Mitochondrion Inner MembranePeripheral Membrane ProteinMatrix Side |
| Alternative ELISA Names | Succinate Dehydrogenase Ubiquinone Iron-Sulfur Subunit - Mitochondrial ELISA kitIron-Sulfur Subunit Of Complex Ii ELISA kitIp ELISA kitMalate Dehydrogenase Quinone Iron-Sulfur Subunit ELISA kitSDHB ELISA kitSDH ELISA kitSDH1 ELISA kit |
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Information sourced from Uniprot.org