Human SCD protein (Recombinant) (N-His) (STJP011496)
SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human SCD-N-His protein was developed from e.coli for the region N-His. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | Reconstitute in sterile water for a stock solution. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at-20 to-80°C for twelve months from the date of receipt. |
Target Information
| Gene Symbol | SCD |
| Gene ID | 6319 |
| Uniprot ID | SCD_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | [Met1-Val72] & [Ala119-Tyr217] & [Val264-Gly359] |
Additional Info
| Function | Stearoyl-CoA desaturase that utilizes O(2) and electrons from reduced cytochrome b5 to introduce the first double bond into saturated fatty acyl-CoA substrates. Catalyzes the insertion of a cis double bond at the delta-9 position into fatty acyl-CoA substrates including palmitoyl-CoA and stearoyl-CoA. Gives rise to a mixture of 16:1 and 18:1 unsaturated fatty acids. Plays an important role in lipid biosynthesis. Plays an important role in regulating the expression of genes that are involved in lipogenesis and in regulating mitochondrial fatty acid oxidation. Plays an important role in body energy homeostasis. Contributes to the biosynthesis of membrane phospholipids, cholesterol esters and triglycerides. |
| Protein Name | Stearoyl-Coa DesaturaseHscd1Acyl-Coa DesaturaseDelta(9-DesaturaseDelta-9 DesaturaseFatty Acid Desaturase |
| Database Links | Reactome: R-HSA-2426168Reactome: R-HSA-75105Reactome: R-HSA-9029558Reactome: R-HSA-9841922 |
| Cellular Localisation | Endoplasmic Reticulum MembraneMulti-Pass Membrane Protein |
| Alternative Protein Names | Stearoyl-Coa Desaturase proteinHscd1 proteinAcyl-Coa Desaturase proteinDelta(9-Desaturase proteinDelta-9 Desaturase proteinFatty Acid Desaturase proteinSCD proteinFADS5 proteinSCD1 proteinSCDOS protein |
Information sourced from Uniprot.org