Human SCARF1 protein (Recombinant-Active) (C-hFc-His) (STJP012108)
SPECIFICATIONS
HostMammalian Cells
ConjugationUnconjugated
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Active-Human SCARF1-C-hFc-His protein was developed from mammalian cells and has a target region of C-hFc-His. For use in research applications. |
| Applications | ELISA/WB |
| Host | Mammalian Cells |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Conjugation | Unconjugated |
| Dilution Range | Reconstitute in sterile water for a stock solution. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 5% Trehalose, 5% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at-20 to-80°C for twelve months from the date of receipt. |
| Endotoxin | <0.1 EU/Mu g of the protein by the LAL method. |
| Immunoreactivity | Measured by its binding ability in a functional ELISA. When human AcLDL is Immobilised at 2 µg/mL (100 µL/well) , recombinant human SCARF1 binds with an ED50 of 5.00-50.0 ng/mL. |
Target Information
| Gene Symbol | SCARF1 |
| Gene ID | 8578 |
| Uniprot ID | SREC_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Ser20-Thr421 |
Additional Info
| Function | Mediates the binding and degradation of acetylated low density lipoprotein (Ac-LDL). Mediates heterophilic interactions, suggesting a function as adhesion protein. Plays a role in the regulation of neurite-like outgrowth. |
| Protein Name | Scavenger Receptor Class F Member 1Acetyl Ldl ReceptorScavenger Receptor Expressed By Endothelial Cells 1Srec-I |
| Database Links | Reactome: R-HSA-3000484 |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane Protein |
| Alternative Protein Names | Scavenger Receptor Class F Member 1 proteinAcetyl Ldl Receptor proteinScavenger Receptor Expressed By Endothelial Cells 1 proteinSrec-I proteinSCARF1 proteinKIAA0149 proteinSREC protein |
Information sourced from Uniprot.org