Human S100A4 (S100A4) Antibody Pair (STJAP00819)
SPECIFICATIONS
ClonalityMonoclonal/Monoclonal
HostRabbit/Rabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenRecombinant protein
General Information
| Short Description | This S100A4 antibody pair contains complimentary capture and detection antibodies, which work together under the principals of the. |
| Applications | ELISA |
| Host | Rabbit/Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal/Monoclonal |
| Clone ID | R54-1P-4/R62-2M-9 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | Affinity Purified |
| Dilution Range | Determined by end user |
| Formulation | 0.01M PBS, pH 7.2 |
| Storage Instruction | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
Target Information
| Gene Symbol | S100A4 |
| Gene ID | 6275 |
| Uniprot ID | S10A4_HUMAN |
| Immunogen | Recombinant protein |
Additional Info
| Tissue Specificity | Ubiquitously expressed. |
| Function | Calcium-binding protein that plays a role in various cellular processes including motility, angiogenesis, cell differentiation, apoptosis, and autophagy. Increases cell motility and invasiveness by interacting with non-muscle myosin heavy chain (NMMHC) IIA/MYH9. Mechanistically, promotes filament depolymerization and increases the amount of soluble myosin-IIA, resulting in the formation of stable protrusions facilitating chemotaxis. Also modulates the pro-apoptotic function of TP53 by binding to its C-terminal transactivation domain within the nucleus and reducing its protein levels. Within the extracellular space, stimulates cytokine production including granulocyte colony-stimulating factor and CCL24 from T-lymphocytes. In addition, stimulates T-lymphocyte chemotaxis by acting as a chemoattractant complex with PGLYRP1 that promotes lymphocyte migration via CCR5 and CXCR3 receptors. |
| Protein Name | Protein S100-A4CalvasculinMetastasinPlacental Calcium-Binding ProteinProtein Mts1S100 Calcium-Binding Protein A4 |
| Database Links | |
| Cellular Localisation | SecretedNucleusCytoplasm |
| Alternative Antibody Pair Names | Protein S100-A4 antibody pairCalvasculin antibody pairMetastasin antibody pairPlacental Calcium-Binding Protein antibody pairProtein Mts1 antibody pairS100 Calcium-Binding Protein A4 antibody pairS100A4 antibody pairCAPL antibody pairMTS1 antibody pair |
Information sourced from Uniprot.org