Human RRM2 protein (Recombinant) (C-His) (STJP013302)
SPECIFICATIONS
HostMammalian Cells
ConjugationUnconjugated
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human RRM2-C-His protein was developed from mammalian cells and has a target region of C-His. For use in research applications. |
| Applications | ELISA/WB |
| Host | Mammalian Cells |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Conjugation | Unconjugated |
| Dilution Range | Reconstitute in sterile water for a stock solution. |
| Formulation | Lyophilized from a 0.22 Mu m filtered solution in 20mM Tris-HCl, 150mM NaCl, 5% Trehalose, pH 8.0. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at-20 to-80°C for twelve months from the date of receipt. |
| Endotoxin | < 1 EU/µg as determined by LAL test. |
Target Information
| Gene Symbol | RRM2 |
| Gene ID | 6241 |
| Uniprot ID | RIR2_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Met1-Phe389 |
Additional Info
| Function | Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. Inhibits Wnt signaling. |
| Protein Name | Ribonucleoside-Diphosphate Reductase Subunit M2Ribonucleotide Reductase Small ChainRibonucleotide Reductase Small Subunit |
| Database Links | Reactome: R-HSA-499943Reactome: R-HSA-69205Reactome: R-HSA-8953750 |
| Cellular Localisation | CytoplasmNucleusLocalized To The Cytoplasm In S Phase CellsMay Localize To The Nucleus In G2 Phase Cells |
| Alternative Protein Names | Ribonucleoside-Diphosphate Reductase Subunit M2 proteinRibonucleotide Reductase Small Chain proteinRibonucleotide Reductase Small Subunit proteinRRM2 proteinRR2 protein |
Information sourced from Uniprot.org