| Function | Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA-precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits. Also functions as a cell surface receptor for laminin. Plays a role in cell adhesion to the basement membrane and in the consequent activation of signaling transduction pathways. May play a role in cell fate determination and tissue morphogenesis. Acts as a PPP1R16B-dependent substrate of PPP1CA. (Microbial infection) Acts as a receptor for the Adeno-associated viruses 2,3,8 and 9. (Microbial infection) Acts as a receptor for the Dengue virus. (Microbial infection) Acts as a receptor for the Sindbis virus. (Microbial infection) Acts as a receptor for the Venezuelan equine encephalitis virus. (Microbial infection) Acts as a receptor for the pathogenic prion protein. (Microbial infection) Acts as a receptor for bacteria. |
| Protein Name | Small Ribosomal Subunit Protein Us237 Kda Laminin Receptor Precursor37lrp37/67 Kda Laminin ReceptorLrp/Lr40s Ribosomal Protein Sa67 Kda Laminin Receptor67lrColon Carcinoma Laminin-Binding ProteinLaminin Receptor 1LamrLaminin-Binding Protein Precursor P40Lbp/P40Multidrug Resistance-Associated Protein Mgr1-AgNem/1chd4 |
| Database Links | Reactome: R-HSA-156827Reactome: R-HSA-156902Reactome: R-HSA-1799339Reactome: R-HSA-192823Reactome: R-HSA-2408557Reactome: R-HSA-6791226Reactome: R-HSA-72649Reactome: R-HSA-72689Reactome: R-HSA-72695Reactome: R-HSA-72702Reactome: R-HSA-72706Reactome: R-HSA-72764Reactome: R-HSA-9010553Reactome: R-HSA-9633012Reactome: R-HSA-9735869Reactome: R-HSA-9754678Reactome: R-HSA-975956Reactome: R-HSA-975957 |
| Cellular Localisation | Cell MembraneCytoplasmNucleus67lr Is Found At The Surface Of The Plasma MembraneWith Its C-Terminal Laminin-Binding Domain Accessible To Extracellular Ligands37lrp Is Found At The Cell SurfaceIn The Cytoplasm And In The NucleusColocalizes With Ppp1r16b In The Cell Membrane |
| Alternative Protein Names | Small Ribosomal Subunit Protein Us2 protein37 Kda Laminin Receptor Precursor protein37lrp protein37/67 Kda Laminin Receptor proteinLrp/Lr protein40s Ribosomal Protein Sa protein67 Kda Laminin Receptor protein67lr proteinColon Carcinoma Laminin-Binding Protein proteinLaminin Receptor 1 proteinLamr proteinLaminin-Binding Protein Precursor P40 proteinLbp/P40 proteinMultidrug Resistance-Associated Protein Mgr1-Ag proteinNem/1chd4 proteinRPSA proteinLAMBR proteinLAMR1 protein |
Information sourced from Uniprot.org
