| Short Description : | Recombinant-Human RPS7-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Applications: | SDS-PAGE |
| Host: | E.coli |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Concentration: | 0.5 mg/mL |
| Formulation: | Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 0.1M NaCl, 30% Glycerol, 1mM DTT |
| Storage Instruction: | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | RPS7 |
| Gene ID: | 6201 |
| Uniprot ID: | RS7_HUMAN |
| Accession Number: | NP_001002 |
| Immunogen: | Human |
| Immunogen Region: | 1-194aa |
| Immunogen Sequence: | MGSSHHHHHH SSGLVPRGSH MGSHMFSSSA KIVKPNGEKP DEFESGISQA LLELEMNSDL KAQLRELNIT AAKEIEVGGG RKAIIIFVPV PQLKSFQKIQ VRLVRELEKK FSGKHVVFIA QRRILPKPTR KSRTKNKQKR PRSRTLTAVH DAILEDLVFP SEIVGKRIRV KLDGSRLIKV HLDKAQQNNV EHKVETFSGV YKKLTGKDVN FEFPEFQL |
| Post Translational Modifications | Phosphorylated by NEK6. Ubiquitinated. Deubiquitinated by DESI2, leading to its stabilization. |
| Function | Component of the small ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. Required for rRNA maturation. Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome. |
| Protein Name | Small Ribosomal Subunit Protein Es740s Ribosomal Protein S7 |
| Database Links | Reactome: R-HSA-156827Reactome: R-HSA-156902Reactome: R-HSA-1799339Reactome: R-HSA-192823Reactome: R-HSA-2408557Reactome: R-HSA-6790901Reactome: R-HSA-6791226Reactome: R-HSA-72649Reactome: R-HSA-72689Reactome: R-HSA-72695Reactome: R-HSA-72702Reactome: R-HSA-72706Reactome: R-HSA-72764Reactome: R-HSA-9010553Reactome: R-HSA-9633012Reactome: R-HSA-9735869Reactome: R-HSA-9754678Reactome: R-HSA-975956Reactome: R-HSA-975957 |
| Cellular Localisation | CytoplasmCytoskeletonMicrotubule Organizing CenterCentrosomeNucleusNucleolusAlthough Rps7 Is Functional Within The CytoplasmThe Assembly Of Ribosomal Subunits Occurs In The NucleusRps7 Nuclear Import Is Mediated By Ipo5/Ranbp5Ipo7/Ranbp7Kpnb1/Importin-Beta Or Tpno1/TrnColocalizes With Nek6 In The Centrosome |
| Alternative Protein Names | Small Ribosomal Subunit Protein Es7 protein40s Ribosomal Protein S7 proteinRPS7 protein |
Information sourced from Uniprot.org
