Human RPRD1A protein (Recombinant) (His-Tag) (STJP018745)
SPECIFICATIONS
HostE.coli
ImmunogenHuman
General Information
| Short Description | Recombinant-Human RPRD1A-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Applications | SDS-PAGE |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Concentration | 0.5 mg/mL |
| Formulation | Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 20% Glycerol, 1mM DTT |
| Storage Instruction | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | RPRD1A |
| Gene ID | 55197 |
| Uniprot ID | RPR1A_HUMAN |
| Accession Number | NP_060640 |
| Immunogen | Human |
| Immunogen Region | 1-312aa |
| Immunogen Sequence | MGSSHHHHHH SSGLVPRGSH MGSEFMSAFS EAALEKKLSE LSNSQQSVQT LSLWLIHHRK HSRPIVTVWE RELRKAKPNR KLTFLYLAND VIQNSKRKGP EFTKDFAPVI VEAFKHVSSE TDESCKKHLG RVLSIWEERS VYENDVLEQL KQALYGDKKP RKRTYEQIKV DENENCSSLG SPSEPPQTLD LVRALQDLEN AASGDAAVHQ RIASLPVEVQ EVSLLDKI |
Additional Info
| Function | Interacts with phosphorylated C-terminal heptapeptide repeat domain (CTD) of the largest RNA polymerase II subunit POLR2A, and participates in dephosphorylation of the CTD by RPAP2. May act as a negative regulator of cyclin-D1 (CCND1) and cyclin-E (CCNE1) in the cell cycle. |
| Protein Name | Regulation Of Nuclear Pre-Mrna Domain-Containing Protein 1aCyclin-Dependent Kinase Inhibitor 2b-Related ProteinP15ink4b-Related Protein |
| Database Links | Reactome: R-HSA-6807505 |
| Cellular Localisation | Nucleus |
| Alternative Protein Names | Regulation Of Nuclear Pre-Mrna Domain-Containing Protein 1a proteinCyclin-Dependent Kinase Inhibitor 2b-Related Protein proteinP15ink4b-Related Protein proteinRPRD1A proteinP15RS protein |
Information sourced from Uniprot.org