Human RPN2 protein (Recombinant) (His-Tag) (STJP018007)
SPECIFICATIONS
HostE.coli
ImmunogenHuman
General Information
| Short Description | Recombinant-Human RPN2-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Applications | SDS-PAGE |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Concentration | 1 mg/mL |
| Formulation | Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 10% Glycerol 0.1M NaCl |
| Storage Instruction | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | RPN2 |
| Gene ID | 6185 |
| Uniprot ID | RPN2_HUMAN |
| Accession Number | NP_002942 |
| Immunogen | Human |
| Immunogen Region | 23-540aa |
| Immunogen Sequence |
Additional Info
| Tissue Specificity | Expressed in all tissues tested. |
| Function | Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity. |
| Protein Name | Dolichyl-Diphosphooligosaccharide--Protein Glycosyltransferase Subunit 2Dolichyl-Diphosphooligosaccharide--Protein Glycosyltransferase 63 Kda SubunitRibiirRibophorin IiRpn-IiRibophorin-2 |
| Database Links | Reactome: R-HSA-1799339Reactome: R-HSA-446203Reactome: R-HSA-9694548 |
| Cellular Localisation | Endoplasmic ReticulumEndoplasmic Reticulum MembraneMulti-Pass Membrane Protein |
| Alternative Protein Names | Dolichyl-Diphosphooligosaccharide--Protein Glycosyltransferase Subunit 2 proteinDolichyl-Diphosphooligosaccharide--Protein Glycosyltransferase 63 Kda Subunit proteinRibiir proteinRibophorin Ii proteinRpn-Ii proteinRibophorin-2 proteinRPN2 protein |
Information sourced from Uniprot.org