Human RPL23A (Ribosomal Protein L23A) Sandwich ELISA Kit (STJE0011940)

SPECIFICATIONS
STJE0011940
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General Information

Short DescriptionThis RPL23A Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human tissue homogenates, cell lysates or other biological fluids..
ApplicationsELISA
ReactivityHuman
Sensitivity0.058ng/mL
Detection Limit0.156-10ng/mL
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

Storage InstructionStore the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time4.5 hrs

Target Information

Gene SymbolRPL23A
Gene ID6147
Uniprot IDRL23A_HUMAN
Sample Typetissue homogenates, cell lysates or other biological fluids.

Additional Info

Tissue Specificity
Post Translational Modifications N-terminus is methylated by METTL11A/NTM1. Citrullinated by PADI4.
Function Component of the large ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. Binds a specific region on the 26S rRNA. May promote p53/TP53 degradation possibly through the stimulation of MDM2-mediated TP53 polyubiquitination.
Protein Name Large Ribosomal Subunit Protein Ul23
60s Ribosomal Protein L23a
Database Links Reactome: R-HSA-156827
Reactome: R-HSA-156902
Reactome: R-HSA-1799339
Reactome: R-HSA-192823
Reactome: R-HSA-2408557
Reactome: R-HSA-6791226
Reactome: R-HSA-72689
Reactome: R-HSA-72706
Reactome: R-HSA-72764
Reactome: R-HSA-9010553
Reactome: R-HSA-9633012
Reactome: R-HSA-975956
Reactome: R-HSA-975957
Cellular Localisation Cytoplasm
Nucleus
Although Rpl23a Is Functional Within The Cytoplasm
The Assembly Of Ribosomal Subunits Occurs In The Nucleus
Rpl23a Nuclear Import Is Mediated By Ipo5/Ranbp5
Ipo7/Ranbp7
Kpnb1/Importin-Beta Or Tpno1/Trn
Alternative ELISA Names Large Ribosomal Subunit Protein Ul23 ELISA kit
60s Ribosomal Protein L23a ELISA kit
RPL23A ELISA kit
output

Information sourced from Uniprot.org

Citations

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