Human RNMTL1 protein (Recombinant) (His-Tag) (STJP019123)
SPECIFICATIONS
HostE.coli
ImmunogenHuman
General Information
| Short Description | Recombinant-Human RNMTL1-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Applications | SDS-PAGE/Denatured |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Concentration | 1 mg/mL |
| Formulation | Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 10% Glycerol |
| Storage Instruction | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | MRM3 |
| Gene ID | 55178 |
| Uniprot ID | MRM3_HUMAN |
| Accession Number | NP_060616 |
| Immunogen | Human |
| Immunogen Region | 1-420aa |
| Immunogen Sequence | MGSSHHHHHH SSGLVPRGSH MGSMAALVRP ARFVVRPLLQ VVQAWDLDAR RWVRALRRSP VKVVFPSGEV VEQKRAPGKQ PRKAPSEASA QEQREKQPLE ESASRAPSTW EESGLRYDKA YPGDRRLSSV MTIVKSRPFR EKQGKILLEG RRLISDALKA GAVPKMFFFS RLEYLKELPV DKLKGVSLIK VKFEDIKDWS DLVTPQGIMG IFAKPDHVKM TYPKTQLQ |
Additional Info
| Tissue Specificity | Expressed at same level in normal liver and hepatocarcinoma. |
| Function | S-adenosyl-L-methionine-dependent 2'-O-ribose methyltransferase that catalyzes the formation of 2'-O-methylguanosine at position 1370 (Gm1370) in the 16S mitochondrial large subunit ribosomal RNA (mtLSU rRNA), a conserved modification in the peptidyl transferase domain of the mtLSU rRNA. Also required for formation of 2'-O-methyluridine at position 1369 (Um1369) mediated by MRM2. |
| Protein Name | Rrna Methyltransferase 3 - Mitochondrial16s RrnaGuanosine(1370-2'-O-Methyltransferase16s Rrna Gm1370 2'-O-MethyltransferaseRna Methyltransferase-Like Protein 1 |
| Database Links | Reactome: R-HSA-6793080 |
| Cellular Localisation | Mitochondrion |
| Alternative Protein Names | Rrna Methyltransferase 3 - Mitochondrial protein16s Rrna proteinGuanosine(1370-2'-O-Methyltransferase protein16s Rrna Gm1370 2'-O-Methyltransferase proteinRna Methyltransferase-Like Protein 1 proteinMRM3 proteinRNMTL1 proteinHC90 protein |
Information sourced from Uniprot.org