Human RNGTT protein (Recombinant) (N-His) (STJP010720)
SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human RNGTT-N-His protein was developed from e.coli for the region N-His. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
Target Information
| Gene Symbol | RNGTT |
| Gene ID | 8732 |
| Uniprot ID | MCE1_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Pro328-Val553 |
Additional Info
| Function | Bifunctional mRNA-capping enzyme exhibiting RNA 5'-triphosphate monophosphatase activity in the N-terminal part and mRNA guanylyltransferase activity in the C-terminal part. Catalyzes the first two steps of cap formation: by removing the gamma-phosphate from the 5'-triphosphate end of nascent mRNA to yield a diphosphate end, and by transferring the GMP moiety of GTP to the 5'-diphosphate terminus of RNA via a covalent enzyme-GMP reaction intermediate. |
| Protein Name | Mrna-Capping EnzymeHcap1Hce Includes - Mrna 5'-Triphosphate MonophosphataseMrna 5'-Phosphatase - Mrna GuanylyltransferaseGtp--Rna GuanylyltransferaseGtase |
| Database Links | Reactome: R-HSA-167160Reactome: R-HSA-72086Reactome: R-HSA-77075 |
| Cellular Localisation | Nucleus |
| Alternative Protein Names | Mrna-Capping Enzyme proteinHcap1 proteinHce Includes - Mrna 5'-Triphosphate Monophosphatase proteinMrna 5'-Phosphatase - Mrna Guanylyltransferase proteinGtp--Rna Guanylyltransferase proteinGtase proteinRNGTT proteinCAP1A protein |
Information sourced from Uniprot.org