| Host: | E.coli |
| Applications: | ELISA/Immunogen/SDS-PAGE/WB |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Recombinant-Human RNASEH1-N-His protein was developed from e.coli and has a target region of N-His. For use in research applications. |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Dilution Range: | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Storage Instruction: | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
| Gene Symbol: | RNASEH1 |
| Gene ID: | 246243 |
| Uniprot ID: | RNH1_HUMAN |
| Immunogen Region: | Asp138-Asp286 |
| Immunogen: | Homo sapiens (Human) |
| Function | Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. Plays a role in RNA polymerase II (RNAp II) transcription termination by degrading R-loop RNA-DNA hybrid formation at G-rich pause sites located downstream of the poly(A) site and behind the elongating RNAp II. |
| Protein Name | Ribonuclease H1Rnase H1Ribonuclease H Type Ii |
| Database Links | Reactome: R-HSA-9913635 |
| Cellular Localisation | Cytoplasm |
| Alternative Protein Names | Ribonuclease H1 proteinRnase H1 proteinRibonuclease H Type Ii proteinRNASEH1 proteinRNH1 protein |
Information sourced from Uniprot.org