Human RNASE7 (Ribonuclease A7) Sandwich ELISA Kit (STJE0011914)
SPECIFICATIONS
General Information
| Short Description | This RNASE7 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human serum, plasma, tissue homogenates or other biological fluids.. |
| Applications | ELISA |
| Reactivity | Human |
| Sensitivity | 0.61ng/mL |
| Detection Limit | 1.56-100ng/mL |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Storage Instruction | Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time | 4.5 hrs |
Target Information
| Gene Symbol | RNASE7 |
| Gene ID | 84659 |
| Uniprot ID | RNAS7_HUMAN |
| Sample Type | serum, plasma, tissue homogenates or other biological fluids. |
Additional Info
| Tissue Specificity | Expressed in collecting ducts in kidney, and in apical uroepithelium in bladder (at protein level). Expressed in various epithelial tissues including skin, respiratory tract, genito-urinary tract and, at a low level, in the gut. Expressed in liver, kidney, skeletal muscle and heart. |
| Post Translational Modifications | |
| Function | Exhibits a potent RNase activity. Has broad-spectrum antimicrobial activity against many pathogenic microorganisms including uropathogenic E.coli (UPEC), and remarkably potent activity (lethal dose of 90% < 30 nM) against a vancomycin resistant Enterococcus faecium. Causes loss of bacterial membrane integrity. Probably contributes to urinary tract sterility. Bactericidal activity is independent of RNase activity. |
| Protein Name | Ribonuclease 7Rnase 7Skin-Derived Antimicrobial Protein 2Sap-2 |
| Database Links | Reactome: R-HSA-6803157 |
| Cellular Localisation | SecretedDetected In Urine |
| Alternative ELISA Names | Ribonuclease 7 ELISA kitRnase 7 ELISA kitSkin-Derived Antimicrobial Protein 2 ELISA kitSap-2 ELISA kitRNASE7 ELISA kitUNQ2516 ELISA kitPRO6006 ELISA kit |
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Information sourced from Uniprot.org