Human RNA polymerase II subunit RPB11-a/POLR2J protein (Recombinant) (His-Tag) (STJP017882)

SPECIFICATIONS
HostE.coli
ImmunogenHuman
STJP017882
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General Information

Short DescriptionRecombinant-Human Rpolymerase II subunit RPB11-a/POLR2J-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications.
ApplicationsSDS-PAGE
HostE.coli
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

Concentration0.5 mg/mL
FormulationLiquid in 20mM Tris-HCl buffer (pH 8.0) containing 0.2M NaCl, 40% Glycerol, 5mM DTT, and 2mM EDTA
Storage InstructionFor short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles.

Target Information

Gene SymbolPOLR2J
Gene ID5439
Uniprot IDRPB11_HUMAN
Accession NumberNP_006225
ImmunogenHuman
Immunogen Region1-117aa
Immunogen SequenceMNAPPAF ESFLLFEGEK KITINKDTKV PNACLFTINK EDHTLGNIIK SQLLKDPQVL FAGYKVPHPL EHKIIIRVQT TPDYSPQEAF TNAITDLISE LSLLEERFRV AIKDKQEGIE

Additional Info

Tissue Specificity Ubiquitously expressed. High expression was found in heart and skeletal muscle.
Function Core component of RNA polymerase II (Pol II), a DNA-dependent RNA polymerase which synthesizes mRNA precursors and many functional non-coding RNAs using the four ribonucleoside triphosphates as substrates.
Protein Name Dna-Directed Rna Polymerase Ii Subunit Rpb11-A
Rna Polymerase Ii Subunit B11-A
Rpb11a
Dna-Directed Rna Polymerase Ii Subunit J-1
Rna Polymerase Ii 13.3 Kda Subunit
Database Links Reactome: R-HSA-112382
Reactome: R-HSA-113418
Reactome: R-HSA-167152
Reactome: R-HSA-167158
Reactome: R-HSA-167160
Reactome: R-HSA-167161
Reactome: R-HSA-167162
Reactome: R-HSA-167172
Reactome: R-HSA-167200
Reactome: R-HSA-167238
Reactome: R-HSA-167242
Reactome: R-HSA-167243
Reactome: R-HSA-167246
Reactome: R-HSA-167287
Reactome: R-HSA-167290
Reactome: R-HSA-168325
Reactome: R-HSA-203927
Reactome: R-HSA-5578749
Reactome: R-HSA-5601884
Reactome: R-HSA-5617472
Reactome: R-HSA-674695
Reactome: R-HSA-6781823
Reactome: R-HSA-6781827
Reactome: R-HSA-6782135
Reactome: R-HSA-6782210
Reactome: R-HSA-6796648
Reactome: R-HSA-6803529
Reactome: R-HSA-6807505
Reactome: R-HSA-72086
Reactome: R-HSA-72163
Reactome: R-HSA-72165
Reactome: R-HSA-72203
Reactome: R-HSA-73776
Reactome: R-HSA-73779
Reactome: R-HSA-75953
Reactome: R-HSA-75955
Reactome: R-HSA-76042
Reactome: R-HSA-77075
Reactome: R-HSA-8851708
Reactome: R-HSA-9018519
Reactome: R-HSA-9670095
Cellular Localisation Nucleus
Alternative Protein Names Dna-Directed Rna Polymerase Ii Subunit Rpb11-A protein
Rna Polymerase Ii Subunit B11-A protein
Rpb11a protein
Dna-Directed Rna Polymerase Ii Subunit J-1 protein
Rna Polymerase Ii 13.3 Kda Subunit protein
POLR2J protein
POLR2J1 protein

Information sourced from Uniprot.org

Citations

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