Human RIOX2 protein (Recombinant) (N-His) (STJP008010)
SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human RIOX2-N-His protein was developed from e.coli for the region N-His. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
Target Information
| Gene Symbol | RIOX2 |
| Gene ID | 84864 |
| Uniprot ID | RIOX2_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Ser37-Ser257 |
Additional Info
| Function | Oxygenase that can act as both a histone lysine demethylase and a ribosomal histidine hydroxylase. Is involved in the demethylation of trimethylated 'Lys-9' on histone H3 (H3K9me3), leading to an increase in ribosomal RNA expression. Also catalyzes the hydroxylation of 60S ribosomal protein L27a on 'His-39'. May play an important role in cell growth and survival. May be involved in ribosome biogenesis, most likely during the assembly process of pre-ribosomal particles. |
| Protein Name | Ribosomal Oxygenase 260s Ribosomal Protein L27a Histidine HydroxylaseBifunctional Lysine-Specific Demethylase And Histidyl-Hydroxylase MinaHistone Lysine Demethylase MinaMyc-Induced Nuclear AntigenMineral Dust-Induced Gene ProteinNucleolar Protein 52Ribosomal Oxygenase MinaRox |
| Database Links | Reactome: R-HSA-3214842Reactome: R-HSA-9629569 |
| Cellular Localisation | NucleusNucleolus |
| Alternative Protein Names | Ribosomal Oxygenase 2 protein60s Ribosomal Protein L27a Histidine Hydroxylase proteinBifunctional Lysine-Specific Demethylase And Histidyl-Hydroxylase Mina proteinHistone Lysine Demethylase Mina proteinMyc-Induced Nuclear Antigen proteinMineral Dust-Induced Gene Protein proteinNucleolar Protein 52 proteinRibosomal Oxygenase Mina proteinRox proteinRIOX2 proteinMDIG proteinMINA proteinMINA53 proteinNO52 protein |
Information sourced from Uniprot.org