Human Ribonuclease A/RNASE 1 protein (Recombinant) (His-Tag) (STJP019485)

Name: Human Ribonuclease A/RNASE 1 protein (Recombinant) (His-Tag) (STJP019485)
SKU: STJP019485
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⇓ Datasheet ⇓ SDS Citations

SPECIFICATIONS

HostHEK293 Cells

ImmunogenHuman

STJP019485

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Short Description	Recombinant-Human Ribonuclease A/RNASE 1-His-Tag protein was developed from hek293 cells and has a target region of His-Tag. For use in research applications.
Applications	SDS-PAGE/Enzyme Activity
Host	HEK293 Cells
Note	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Concentration	1 mg/mL
Formulation	Liquid In Phosphate-Buffered Saline (pH 7.4) containing 10% Glycerol
Storage Instruction	For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles.
Endotoxin	< 1 EU per 1ug of protein (determined by LAL method)
Immunoreactivity	Specific activity is > 5 X 10^4 unit/mg, and is defined as the amount of enzyme that cleaves 1.0 pmole of RNase probe per minute at 25C.

Gene Symbol	RNASE1
Gene ID	6035
Uniprot ID	RNAS1_HUMAN
Accession Number	NP_937878.1
Immunogen	Human
Immunogen Region	29-156aa
Immunogen Sequence	KESRAKKFQR QHMDSDSSPS SSSTYCNQMM RRRNMTQGRC KPVNTFVHEP LVDVQNVCFQ EKVTCKNGQG NCYKSNSSMH ITDCRLTNGS RYPNCAYRTS PKERHIIVAC EGSPYVPVHF DASVEDST

Tissue Specificity	Pancreas and other tissues and body fluids (indicating it may have other physiological functions besides its role in digestion).
Post Translational Modifications	N-linked glycans are of complex type.
Function	Endonuclease that catalyzes the cleavage of RNA on the 3' side of pyrimidine nucleotides. Acts on single-stranded and double-stranded RNA.
Protein Name	Ribonuclease Pancreatic Hp-Rnase Rib-1 Rnase Upi-1 Ribonuclease 1 Rnase 1 Ribonuclease A Rnase A
Database Links	Reactome: R-HSA-9613829 Reactome: R-HSA-9615710 Reactome: R-HSA-9925561
Cellular Localisation	Secreted
Alternative Protein Names	Ribonuclease Pancreatic protein Hp-Rnase protein Rib-1 protein Rnase Upi-1 protein Ribonuclease 1 protein Rnase 1 protein Ribonuclease A protein Rnase A protein RNASE1 protein RIB1 protein RNS1 protein

Information sourced from Uniprot.org