Human Ribonuclease 3/ECP (Ribonuclease 3/ECP) Antibody Pair (STJAP00912)
General Information
| Short Description | This Ribonuclease 3/ECP antibody pair contains complimentary capture and detection antibodies, which work together under the principals of the. |
| Applications | ELISA |
| Host | Rabbit/Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal/Monoclonal |
| Clone ID | R05-6G-2/R02-8A-5 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | Affinity Purification |
| Dilution Range | Determined by end user |
| Formulation | 0.01M PBS, pH 7.2 |
| Storage Instruction | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
Target Information
| Gene Symbol | RNASE3 |
| Gene ID | 6037 |
| Uniprot ID | ECP_HUMAN |
| Immunogen | Recombinant protein |
Additional Info
| Function | Cytotoxin and helminthotoxin with low-efficiency ribonuclease activity. Possesses a wide variety of biological activities. Exhibits antibacterial activity, including cytoplasmic membrane depolarization of preferentially Gram-negative, but also Gram-positive strains. Promotes E.coli outer membrane detachment, alteration of the overall cell shape and partial loss of cell content. |
| Protein Name | Eosinophil Cationic ProteinEcpRibonuclease 3Rnase 3 |
| Database Links | Reactome: R-HSA-6798695Reactome: R-HSA-6803157 |
| Cellular Localisation | SecretedLocated In The Matrix Of Eosinophil Large Specific GranuleWhich Are Released Following Activation By An Immune Stimulus |
| Alternative Antibody Pair Names | Eosinophil Cationic Protein antibody pairEcp antibody pairRibonuclease 3 antibody pairRnase 3 antibody pairRNASE3 antibody pairECP antibody pairRNS3 antibody pair |
Information sourced from Uniprot.org
Citations
Product Review
Frequently Asked Questions
Common questions about Human Ribonuclease 3/ECP (Ribonuclease 3/ECP) Antibody Pair (STJAP00912)
This antibody pair detects human Ribonuclease 3, also known as Eosinophil Cationic Protein (ECP), corresponding to UniProt entry P12724. Reactivity has been confirmed for human samples only.
Both antibodies are rabbit monoclonals, with clone IDs R05-6G-2 and R02-8A-5. Both are unconjugated IgG antibodies purified by affinity chromatography.
This antibody pair is validated for use in ELISA. It is intended for sandwich ELISA development where one clone serves as the capture antibody and the other as the detection antibody.
Both antibodies are formulated in 0.01M PBS at pH 7.2. They should be stored at 4°C for short-term use, aliquoted, and stored at -20°C for long-term storage, with repeated freeze/thaw cycles avoided.
Working concentrations for both the capture and detection antibodies are to be determined by the end user. Optimization of antibody concentrations is required as part of the user's assay development process.
Orders typically arrive within 1 to 2 weeks, and often sooner depending on your location. If your timeline is critical, please contact us before ordering and we can advise on current lead times.
This product is shipped on gel ice packs to maintain integrity during transit. Priority shipping is used as standard to minimise time in transit.
A Certificate of Analysis (CoA) is provided with every order. If you do not receive one, please contact us and we will issue it promptly.