Human RGS19 protein (Recombinant) (His-Tag) (STJP016949)

Name: Human RGS19 protein (Recombinant) (His-Tag) (STJP016949)
SKU: STJP016949
Availability: InStock

⇓ Datasheet ⇓ SDS Citations

SPECIFICATIONS

HostE.coli

ImmunogenHuman

STJP016949

Current Stock:

🚚 Free UK Delivery on orders over £150

Quantity:

Processing The item has been added

Enquire For Bulk Order

✓ 1-Year Performance Guarantee | SDS & Datasheet Included | Expert Tech Support | Covered by St John's Laboratory Guarantee

Short Description	Recombinant-Human RGS19-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications.
Applications	SDS-PAGE
Host	E.coli
Note	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Concentration	0.5 mg/mL
Formulation	Liquid in phosphate-Buffered Saline (pH 7.4) containing 10% Glycerol
Storage Instruction	For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles.

Gene Symbol	RGS19
Gene ID	10287
Uniprot ID	RGS19_HUMAN
Accession Number	NP_001034556
Immunogen	Human
Immunogen Region	1-217aa
Immunogen Sequence	MGSSHHHHHH SSGLVPRGSH MPTPHEAEKQ ITGPEEADRP PSMSSHDTAS PAAPSRNPCC LCWCCCCSCS WNQERRRAWQ ASRESKLQPL PSCEVCATPS PEEVQSWAQS FDKLMHSPAG RSVFRAFLRT EYSEENMLFW LACEELKAEA NQHVVDEKAR LIYEDYVSIL SPKEVSLDSR VREGINKKMQ EPSAHTFDDA QLQIYTLMHR DSYPRFLSSP TYRALLLQ

Tissue Specificity	Highest expression in lung. Placenta, liver and heart also express high levels of GAIP.
Post Translational Modifications	Fatty acylated. Heavily palmitoylated in the cysteine string motif. Phosphorylated, mainly on serine residues.
Function	Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Binds to G-alpha subfamily 1 members, with the order G(i)a3 > G(i)a1 > G(o)a >> G(z)a/G(i)a2. Activity on G(z)-alpha is inhibited by phosphorylation and palmitoylation of the G-protein.
Protein Name	Regulator Of G-Protein Signaling 19 Rgs19 G-Alpha-Interacting Protein Gaip
Database Links	Reactome: R-HSA-416476 Reactome: R-HSA-418594 Reactome: R-HSA-418597
Cellular Localisation	Membrane Lipid-Anchor
Alternative Protein Names	Regulator Of G-Protein Signaling 19 protein Rgs19 protein G-Alpha-Interacting Protein protein Gaip protein RGS19 protein GAIP protein GNAI3IP protein

Information sourced from Uniprot.org