Human RFK (Riboflavin Kinase) Sandwich ELISA Kit Ready-To-Use Kit (STJE0018264)

Name: Human RFK (Riboflavin Kinase) Sandwich ELISA Kit Ready-To-Use Kit (STJE0018264)
SKU: STJE0018264
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SPECIFICATIONS

STJE0018264

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Short Description	This RFK Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human tissue homogenates, cell lysates or other biological fluids..
Applications	ELISA
Reactivity	Human
Sensitivity	0.27ng/mL
Detection Limit	0.781-50ng/mL
Note	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Storage Instruction	The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time	3 hrs

Gene Symbol	RFK
Gene ID	55312
Uniprot ID	RIFK_HUMAN
Immunogen Region	Ready-To-Use
Sample Type	tissue homogenates, cell lysates or other biological fluids.

Tissue Specificity	Detected in brain, placenta and urinary bladder.
Post Translational Modifications
Function	Catalyzes the phosphorylation of riboflavin (vitamin B2) to form flavin-mononucleotide (FMN), hence rate-limiting enzyme in the synthesis of FAD. Essential for TNF-induced reactive oxygen species (ROS) production. Through its interaction with both TNFRSF1A and CYBA, physically and functionally couples TNFRSF1A to NADPH oxidase. TNF-activation of RFK may enhance the incorporation of FAD in NADPH oxidase, a critical step for the assembly and activation of NADPH oxidase.
Protein Name	Riboflavin Kinase Atp -Riboflavin 5'-Phosphotransferase Flavokinase
Database Links	Reactome: R-HSA-196843
Cellular Localisation	Cytoplasm
Alternative ELISA Names	Riboflavin Kinase ELISA kit Atp -Riboflavin 5'-Phosphotransferase ELISA kit Flavokinase ELISA kit RFK ELISA kit
output

Information sourced from Uniprot.org