Human Resistin/RETN protein (Recombinant) (His-Tag) (STJP018610)
SPECIFICATIONS
HostE.coli
ImmunogenHuman
General Information
| Short Description | Recombinant-Human Resistin/RETN-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Applications | SDS-PAGE/Denatured |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Concentration | 0.5 mg/mL |
| Formulation | Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 0.4M urea, 10% Glycerol |
| Storage Instruction | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | RETN |
| Gene ID | 56729 |
| Uniprot ID | RETN_HUMAN |
| Accession Number | NP_065148 |
| Immunogen | Human |
| Immunogen Region | 19-108aa |
| Immunogen Sequence | MGSSHHHHHH SSGLVPRGSH MKTLCSMEEA INERIQEVAG SLIFRAISSI GLECQSVTSR GDLATCPRGF AVTGCTCGSA CGSWDVRAET TCHCQCAGMD WTGARCCRVQ P |
Additional Info
| Tissue Specificity | Expressed in white adipose tissue (at protein level). Widely expressed, with particularly strong expression in lung, bone marrow, breast and peripheral blood. Expressed strongly in bone marrow and at lower levels in lung, but not detected in other tissues. Isoform 2 is detected in adipose tissue, bone marrow, brain, lung, peripheral blood, placenta and thymus. |
| Function | Hormone that seems to suppress insulin ability to stimulate glucose uptake into adipose cells. Potentially links obesity to diabetes. Promotes chemotaxis in myeloid cells. |
| Protein Name | ResistinAdipose Tissue-Specific Secretory FactorAdsfC/Ebp-Epsilon-Regulated Myeloid-Specific Secreted Cysteine-Rich ProteinCysteine-Rich Secreted Protein A12-Alpha-Like 2Cysteine-Rich Secreted Protein Fizz3 |
| Database Links | Reactome: R-HSA-6798695Reactome: R-HSA-9615017 |
| Cellular Localisation | Secreted |
| Alternative Protein Names | Resistin proteinAdipose Tissue-Specific Secretory Factor proteinAdsf proteinC/Ebp-Epsilon-Regulated Myeloid-Specific Secreted Cysteine-Rich Protein proteinCysteine-Rich Secreted Protein A12-Alpha-Like 2 proteinCysteine-Rich Secreted Protein Fizz3 proteinRETN proteinFIZZ3 proteinHXCP1 proteinRSTN proteinUNQ407 proteinPRO1199 protein |
Information sourced from Uniprot.org