Human RARb (Retinoic Acid Receptor Beta) Sandwich ELISA Kit (STJE0011833)
SPECIFICATIONS
General Information
| Short Description | This RARb Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human tissue homogenates, cell lysates or other biological fluids.. |
| Applications | ELISA |
| Reactivity | Human |
| Sensitivity | 0.057ng/mL |
| Detection Limit | 0.156-10ng/mL |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Storage Instruction | Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time | 4.5 hrs |
Target Information
| Gene Symbol | RARB |
| Gene ID | 5915 |
| Uniprot ID | RARB_HUMAN |
| Sample Type | tissue homogenates, cell lysates or other biological fluids. |
Additional Info
| Tissue Specificity | Expressed in aortic endothelial cells (at protein level). |
| Post Translational Modifications | |
| Function | Receptor for retinoic acid. Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and regulate gene expression in various biological processes. The RXR/RAR heterodimers bind to the retinoic acid response elements (RARE) composed of tandem 5'-AGGTCA-3' sites known as DR1-DR5. In the absence or presence of hormone ligand, acts mainly as an activator of gene expression due to weak binding to corepressors. The RXRA/RARB heterodimer can act as a repressor on the DR1 element and as an activator on the DR5 element. In concert with RARG, required for skeletal growth, matrix homeostasis and growth plate function. |
| Protein Name | Retinoic Acid Receptor BetaRar-BetaHbv-Activated ProteinNuclear Receptor Subfamily 1 Group B Member 2Rar-Epsilon |
| Database Links | Reactome: R-HSA-383280Reactome: R-HSA-5362517Reactome: R-HSA-5617472 |
| Cellular Localisation | NucleusCytoplasmIsoform Beta-1: NucleusIsoform Beta-2: NucleusIsoform Beta-4: Cytoplasm |
| Alternative ELISA Names | Retinoic Acid Receptor Beta ELISA kitRar-Beta ELISA kitHbv-Activated Protein ELISA kitNuclear Receptor Subfamily 1 Group B Member 2 ELISA kitRar-Epsilon ELISA kitRARB ELISA kitHAP ELISA kitNR1B2 ELISA kit |
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Information sourced from Uniprot.org