Human RABGEF1 protein (Recombinant) (N-His) (STJP007920)
SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human RABGEF1-N-His protein was developed from e.coli for the region N-His. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
Target Information
| Gene Symbol | RABGEF1 |
| Gene ID | 27342 |
| Uniprot ID | RABX5_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Thr131-Lys368 |
Additional Info
| Function | Rab effector protein acting as linker between gamma-adaptin, RAB4A or RAB5A. Involved in endocytic membrane fusion and membrane trafficking of recycling endosomes. Stimulates nucleotide exchange on RAB5A. Can act as a ubiquitin ligase. |
| Protein Name | Rab5 Gdp/Gtp Exchange FactorRap1Rabaptin-5-Associated Exchange Factor For Rab5Rabex-5 |
| Database Links | Reactome: R-HSA-8854214Reactome: R-HSA-8876198 |
| Cellular Localisation | CytoplasmEarly EndosomeRecycling Endosome |
| Alternative Protein Names | Rab5 Gdp/Gtp Exchange Factor proteinRap1 proteinRabaptin-5-Associated Exchange Factor For Rab5 proteinRabex-5 proteinRABGEF1 proteinRABEX5 protein |
Information sourced from Uniprot.org