Human RAB27B protein (Recombinant) (His-Tag) (STJP017001)
SPECIFICATIONS
HostE.coli
ImmunogenHuman
General Information
| Short Description | Recombinant-Human RAB27B-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Applications | SDS-PAGE |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Concentration | 1 mg/mL |
| Formulation | Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 0.1M Nacl, 1mM DTT, 10% Glycerol |
| Storage Instruction | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | RAB27B |
| Gene ID | 5874 |
| Uniprot ID | RB27B_HUMAN |
| Accession Number | NP_004154 |
| Immunogen | Human |
| Immunogen Region | 1-218aa |
| Immunogen Sequence |
Additional Info
| Tissue Specificity | Expressed primarily in testis. |
| Function | Small GTPase which cycles between active GTP-bound and inactive GDP-bound states. In its active state, binds to a variety of effector proteins to regulate homeostasis of late endocytic pathway, including endosomal positioning, maturation and secretion. Plays a role in NTRK2/TRKB axonal anterograde transport by facilitating the association of NTRK2/TRKB with KLC1. May be involved in targeting uroplakins to urothelial apical membranes. |
| Protein Name | Ras-Related Protein Rab-27bC25kg |
| Database Links | Reactome: R-HSA-114608Reactome: R-HSA-8873719Reactome: R-HSA-8876198 |
| Cellular Localisation | MembraneLipid-AnchorLate Endosome |
| Alternative Protein Names | Ras-Related Protein Rab-27b proteinC25kg proteinRAB27B protein |
Information sourced from Uniprot.org