Human QSOX1 protein (Recombinant) (N-His) (STJP003148)

SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
STJP003148
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General Information

Short DescriptionRecombinant-Human QSOX1-N-His protein was developed from e.coli for the region N-His. For use in research applications.
ApplicationsELISA/Immunogen/SDS-PAGE/WB
HostE.coli
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

Dilution RangeReconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
FormulationLyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage InstructionUse a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.

Target Information

Gene SymbolQSOX1
Gene ID5768
Uniprot IDQSOX1_HUMAN
ImmunogenHomo sapiens (Human)
Immunogen RegionSer37-Ala181

Additional Info

Post Translational Modifications N-glycosylated. O-glycosylated on Thr and Ser residues.
Function Catalyzes the oxidation of sulfhydryl groups in peptide and protein thiols to disulfides with the reduction of oxygen to hydrogen peroxide. Plays a role in disulfide bond formation in a variety of extracellular proteins. In fibroblasts, required for normal incorporation of laminin into the extracellular matrix, and thereby for normal cell-cell adhesion and cell migration.
Protein Name Sulfhydryl Oxidase 1
Hqsox
Quiescin Q6
Database Links Reactome: R-HSA-114608
Reactome: R-HSA-381426
Reactome: R-HSA-6798695
Reactome: R-HSA-8957275
Cellular Localisation Isoform 1: Golgi Apparatus Membrane
Single-Pass Membrane Protein
Secreted
A Small Proportion Is Secreted
Probably Via A Proteolytic Cleavage That Removes The Membrane Anchor
Isoform 2: Secreted
Found In The Extracellular Medium Of Quiescent Cells But Is Not Found In Proliferating Cells
Alternative Protein Names Sulfhydryl Oxidase 1 protein
Hqsox protein
Quiescin Q6 protein
QSOX1 protein
QSCN6 protein
UNQ2520 protein
PRO6013 protein

Information sourced from Uniprot.org

Citations

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