Tissue Specificity | |
Post Translational Modifications | |
Function | Responsible for the biosynthesis of pyroglutamyl peptides. Has a bias against acidic and tryptophan residues adjacent to the N-terminal glutaminyl residue and a lack of importance of chain length after the second residue. Also catalyzes N-terminal pyroglutamate formation. In vitro, catalyzes pyroglutamate formation of N-terminally truncated form of APP amyloid-beta peptides Glu-3-amyloid-beta. May be involved in the N-terminal pyroglutamate formation of several amyloid-related plaque-forming peptides. |
Protein Name | Glutaminyl-Peptide CyclotransferaseGlutaminyl CyclaseQcSqcGlutaminyl-Trna CyclotransferaseGlutamyl CyclaseEc |
Database Links | Reactome: R-HSA-6798695 |
Cellular Localisation | Secreted |
Alternative ELISA Names | Glutaminyl-Peptide Cyclotransferase ELISA kitGlutaminyl Cyclase ELISA kitQc ELISA kitSqc ELISA kitGlutaminyl-Trna Cyclotransferase ELISA kitGlutamyl Cyclase ELISA kitEc ELISA kitQPCT ELISA kit |
output | |
Information sourced from Uniprot.org