Human PTPRZ1 protein (Recombinant) (N-His) (STJP004377)

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STJP004377
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human PTPRZ1-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: PTPRZ1
Gene ID: 5803
Uniprot ID: PTPRZ_HUMAN
Immunogen Region: Leu32-Glu189
Immunogen: Homo sapiens (Human)
Function Protein tyrosine phosphatase that negatively regulates oligodendrocyte precursor proliferation in the embryonic spinal cord. Required for normal differentiation of the precursor cells into mature, fully myelinating oligodendrocytes. May play a role in protecting oligondendrocytes against apoptosis. May play a role in the establishment of contextual memory, probably via the dephosphorylation of proteins that are part of important signaling cascades.
Protein Name Receptor-Type Tyrosine-Protein Phosphatase Zeta
R-Ptp-Zeta
Protein-Tyrosine Phosphatase Receptor Type Z Polypeptide 1
Protein-Tyrosine Phosphatase Receptor Type Z Polypeptide 2
R-Ptp-Zeta-2
Database Links Reactome: R-HSA-449836
Reactome: R-HSA-9851151
Cellular Localisation Isoform 1: Cell Membrane
Single-Pass Type I Membrane Protein
Secreted
A Secreted Form Is Apparently Generated By Shedding Of The Extracellular Domain
Isoform 2: Secreted
Alternative Protein Names Receptor-Type Tyrosine-Protein Phosphatase Zeta protein
R-Ptp-Zeta protein
Protein-Tyrosine Phosphatase Receptor Type Z Polypeptide 1 protein
Protein-Tyrosine Phosphatase Receptor Type Z Polypeptide 2 protein
R-Ptp-Zeta-2 protein
PTPRZ1 protein
HTPZP2 protein
PTPRZ protein
PTPRZ2 protein
PTPZ protein

Information sourced from Uniprot.org