Human PTHR1 (Parathyroid Hormone Receptor 1) Sandwich ELISA Kit Ready-To-Use Kit (STJE0018132)
SPECIFICATIONS
General Information
| Short Description | This PTHR1 Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human tissue homogenates, cell lysates or other biological fluids.. |
| Applications | ELISA |
| Reactivity | Human |
| Sensitivity | 0.124ng/mL |
| Detection Limit | 0.312-20ng/mL |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Storage Instruction | The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time | 3 hrs |
Target Information
| Gene Symbol | PTH1R |
| Gene ID | 5745 |
| Uniprot ID | PTH1R_HUMAN |
| Immunogen Region | Ready-To-Use |
| Sample Type | tissue homogenates, cell lysates or other biological fluids. |
Additional Info
| Tissue Specificity | Expressed in most tissues. Most abundant in kidney, bone and liver. |
| Post Translational Modifications | N-glycosylated. |
| Function | G-protein-coupled receptor for parathyroid hormone (PTH) and for parathyroid hormone-related peptide (PTHLH). Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of downstream effectors, such as adenylate cyclase (cAMP). PTH1R is coupled to G(s) G alpha proteins and mediates activation of adenylate cyclase activity. PTHLH dissociates from PTH1R more rapidly than PTH.as consequence, the cAMP response induced by PTHLH decays faster than the response induced by PTH. |
| Protein Name | Parathyroid Hormone/Parathyroid Hormone-Related Peptide ReceptorPth/Pthrp Type I ReceptorPth/Pthr ReceptorParathyroid Hormone 1 ReceptorPth1 Receptor |
| Database Links | Reactome: R-HSA-373080Reactome: R-HSA-418555 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative ELISA Names | Parathyroid Hormone/Parathyroid Hormone-Related Peptide Receptor ELISA kitPth/Pthrp Type I Receptor ELISA kitPth/Pthr Receptor ELISA kitParathyroid Hormone 1 Receptor ELISA kitPth1 Receptor ELISA kitPTH1R ELISA kitPTHR ELISA kitPTHR1 ELISA kit |
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Information sourced from Uniprot.org