Human PSRC1 protein (Recombinant) (N-His-KSI) (STJP016042)
SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human PSRC1-N-His-KSI protein was developed from e.coli for the region N-His-KSI. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
| Endotoxin | Please contact us for further information. |
Target Information
| Gene Symbol | PSRC1 |
| Gene ID | 84722 |
| Uniprot ID | PSRC1_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Glu2-Arg363 |
Additional Info
| Post Translational Modifications | Phosphorylated during mitosis. |
| Function | Required for normal progression through mitosis. Required for normal congress of chromosomes at the metaphase plate, and for normal rate of chromosomal segregation during anaphase. Plays a role in the regulation of mitotic spindle dynamics. Increases the rate of turnover of microtubules on metaphase spindles, and contributes to the generation of normal tension across sister kinetochores. Recruits KIF2A and ANKRD53 to the mitotic spindle and spindle poles. May participate in p53/TP53-regulated growth suppression. |
| Protein Name | Proline/Serine-Rich Coiled-Coil Protein 1 |
| Database Links | |
| Cellular Localisation | CytoplasmCytoskeletonSpindleSpindle PoleDetected At The Mitotic Spindle And Spindle PolesDiffusely Distributed Throughout The Cell During Interphase |
| Alternative Protein Names | Proline/Serine-Rich Coiled-Coil Protein 1 proteinPSRC1 proteinDDA3 proteinFP3214 protein |
Information sourced from Uniprot.org