Human PSMD4 (Proteasome 26S Subunit, Non ATPase 4) Sandwich ELISA Kit (STJE0011716)
SPECIFICATIONS
General Information
| Short Description | This PSMD4 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human serum, plasma, tissue homogenates or other biological fluids.. |
| Applications | ELISA |
| Reactivity | Human |
| Sensitivity | 29.8pg/mL |
| Detection Limit | 78-5000pg/ml |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Storage Instruction | Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time | 4.5 hrs |
Target Information
| Gene Symbol | PSMD4 |
| Gene ID | 5710 |
| Uniprot ID | PSMD4_HUMAN |
| Sample Type | serum, plasma, tissue homogenates or other biological fluids. |
Additional Info
| Tissue Specificity | |
| Post Translational Modifications | |
| Function | Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair. PSMD4 acts as an ubiquitin receptor subunit through ubiquitin-interacting motifs and selects ubiquitin-conjugates for destruction. Displays a preferred selectivity for longer polyubiquitin chains. |
| Protein Name | 26s Proteasome Non-Atpase Regulatory Subunit 426s Proteasome Regulatory Subunit Rpn1026s Proteasome Regulatory Subunit S5aAntisecretory Factor 1AfAsfMultiubiquitin Chain-Binding Protein |
| Database Links | Reactome: R-HSA-9907900 |
| Cellular Localisation | |
| Alternative ELISA Names | 26s Proteasome Non-Atpase Regulatory Subunit 4 ELISA kit26s Proteasome Regulatory Subunit Rpn10 ELISA kit26s Proteasome Regulatory Subunit S5a ELISA kitAntisecretory Factor 1 ELISA kitAf ELISA kitAsf ELISA kitMultiubiquitin Chain-Binding Protein ELISA kitPSMD4 ELISA kitMCB1 ELISA kit |
| output |
Information sourced from Uniprot.org