Human PRPF8 protein (Recombinant) (N-His) (STJP008124)
SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human PRPF8-N-His protein was developed from e.coli for the region N-His. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
Target Information
| Gene Symbol | PRPF8 |
| Gene ID | 10594 |
| Uniprot ID | PRP8_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Thr2071-Ala2335 |
Additional Info
| Function | Plays a role in pre-mRNA splicing as core component of precatalytic, catalytic and postcatalytic spliceosomal complexes, both of the predominant U2-type spliceosome and the minor U12-type spliceosome. Functions as a scaffold that mediates the ordered assembly of spliceosomal proteins and snRNAs. Required for the assembly of the U4/U6-U5 tri-snRNP complex, a building block of the spliceosome. Functions as a scaffold that positions spliceosomal U2, U5 and U6 snRNAs at splice sites on pre-mRNA substrates, so that splicing can occur. Interacts with both the 5' and the 3' splice site. |
| Protein Name | Pre-Mrna-Processing-Splicing Factor 8220 Kda U5 Snrnp-Specific ProteinPrp8 HomologSplicing Factor Prp8P220 |
| Database Links | Reactome: R-HSA-72163Reactome: R-HSA-72165 |
| Cellular Localisation | NucleusNucleus Speckle |
| Alternative Protein Names | Pre-Mrna-Processing-Splicing Factor 8 protein220 Kda U5 Snrnp-Specific Protein proteinPrp8 Homolog proteinSplicing Factor Prp8 proteinP220 proteinPRPF8 proteinPRPC8 protein |
Information sourced from Uniprot.org