Human Proinsulin protein (Recombinant) (His-Tag) (STJP019395)
SPECIFICATIONS
HostE.coli
ImmunogenHuman
General Information
| Short Description | Recombinant-Human Proinsulin-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Applications | SDS-PAGE/Bioactivity |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Concentration | 0.5 mg/mL |
| Formulation | Liquid in phosphate-Buffered Saline (pH 7.4) containing 10% Glycerol |
| Storage Instruction | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
| Endotoxin | < 1 EU per 1ug of protein (determined by LAL method) |
| Immunoreactivity | Measured in a cell proliferation assay using MCF7 human breast cancer cell. The ED50 range ≤ 4ug/ml. |
Target Information
| Gene Symbol | INS |
| Gene ID | 3630 |
| Uniprot ID | INS_HUMAN |
| Accession Number | NP_000198 |
| Immunogen | Human |
| Immunogen Region | 25-110aa |
| Immunogen Sequence |
Additional Info
| Function | Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. |
| Protein Name | Insulin Cleaved Into - Insulin B Chain - Insulin A Chain |
| Database Links | Reactome: R-HSA-210745Reactome: R-HSA-264876Reactome: R-HSA-422085Reactome: R-HSA-422356Reactome: R-HSA-6807878Reactome: R-HSA-6811558Reactome: R-HSA-74713Reactome: R-HSA-74749Reactome: R-HSA-74751Reactome: R-HSA-74752Reactome: R-HSA-77387Reactome: R-HSA-9615017Reactome: R-HSA-9768919Reactome: R-HSA-977225 |
| Cellular Localisation | Secreted |
| Alternative Protein Names | Insulin Cleaved Into - Insulin B Chain - Insulin A Chain proteinINS protein |
Information sourced from Uniprot.org