Human PRDX4 (Peroxiredoxin 4) Sandwich ELISA Kit (STJE0011647)
SPECIFICATIONS
General Information
| Short Description | This PRDX4 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human serum, plasma or other biological fluids.. |
| Applications | ELISA |
| Reactivity | Human |
| Sensitivity | 12.3pg/mL |
| Detection Limit | 31.2-2000pg/mL |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Storage Instruction | Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time | 4.5 hrs |
Target Information
| Gene Symbol | PRDX4 |
| Gene ID | 10549 |
| Uniprot ID | PRDX4_HUMAN |
| Sample Type | serum, plasma or other biological fluids. |
Additional Info
| Tissue Specificity | |
| Post Translational Modifications | The enzyme can be inactivated by further oxidation of the cysteine sulfenic acid (C(P)-SOH) to sulphinic acid (C(P)-SO2H) and sulphonic acid (C(P)-SO3H) instead of its condensation to a disulfide bond. |
| Function | Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides and as sensor of hydrogen peroxide-mediated signaling events. Regulates the activation of NF-kappa-B in the cytosol by a modulation of I-kappa-B-alpha phosphorylation. |
| Protein Name | Peroxiredoxin-4Antioxidant Enzyme Aoe372Aoe37-2Peroxiredoxin IvPrx-IvThioredoxin Peroxidase Ao372Thioredoxin-Dependent Peroxide Reductase A0372Thioredoxin-Dependent Peroxiredoxin 4 |
| Database Links | Reactome: R-HSA-6798695 |
| Cellular Localisation | CytoplasmEndoplasmic ReticulumCotranslationally Translocated To And Retained Within The Endoplasmic ReticulumA Small Fraction Of The Protein Is Cytoplasmic |
| Alternative ELISA Names | Peroxiredoxin-4 ELISA kitAntioxidant Enzyme Aoe372 ELISA kitAoe37-2 ELISA kitPeroxiredoxin Iv ELISA kitPrx-Iv ELISA kitThioredoxin Peroxidase Ao372 ELISA kitThioredoxin-Dependent Peroxide Reductase A0372 ELISA kitThioredoxin-Dependent Peroxiredoxin 4 ELISA kitPRDX4 ELISA kit |
| output |
Information sourced from Uniprot.org