Human PRDX3 protein (Recombinant) (Tag free) (STJP014473)
SPECIFICATIONS
HostE.coli
ConjugationUnconjugated
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human PRDX3-Tag free protein was developed from e.coli and has a target region of Tag free. For use in research applications. |
| Applications | ELISA/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Conjugation | Unconjugated |
| Formulation | Supplied as a 0.22 Mu m filtered solution in 20mM Tris-HCl, pH 8.0. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8ยฐC for one week. Store at-20 to-80ยฐC for twelve months from the date of receipt. |
| Endotoxin | < 1 EU/ยตg as determined by LAL test. |
Target Information
| Gene Symbol | PRDX3 |
| Gene ID | 10935 |
| Uniprot ID | PRDX3_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Pro63-Gln256 |
Additional Info
| Function | Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides. Acts synergistically with MAP3K13 to regulate the activation of NF-kappa-B in the cytosol. Required for the maintenance of physical strength. |
| Protein Name | Thioredoxin-Dependent Peroxide Reductase - MitochondrialAntioxidant Protein 1Aop-1Hbc189Peroxiredoxin IiiPrx-IiiPeroxiredoxin-3Protein Mer5 HomologThioredoxin-Dependent Peroxiredoxin 3 |
| Database Links | Reactome: R-HSA-3299685 |
| Cellular Localisation | MitochondrionCytoplasmEarly EndosomeLocalizes To Early Endosomes In A Rps6kc1-Dependent Manner |
| Alternative Protein Names | Thioredoxin-Dependent Peroxide Reductase - Mitochondrial proteinAntioxidant Protein 1 proteinAop-1 proteinHbc189 proteinPeroxiredoxin Iii proteinPrx-Iii proteinPeroxiredoxin-3 proteinProtein Mer5 Homolog proteinThioredoxin-Dependent Peroxiredoxin 3 proteinPRDX3 proteinAOP1 protein |
Information sourced from Uniprot.org