Human PRDX2 (Peroxiredoxin 2) Sandwich ELISA Kit Ready-To-Use Kit (STJE0018032)
SPECIFICATIONS
General Information
| Short Description | This PRDX2 Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human serum, plasma, tissue homogenates or other biological fluids.. |
| Applications | ELISA |
| Reactivity | Human |
| Sensitivity | 0.35ng/mL |
| Detection Limit | 0.781-50ng/mL |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Storage Instruction | The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time | 3 hrs |
Target Information
| Gene Symbol | PRDX2 |
| Gene ID | 7001 |
| Uniprot ID | PRDX2_HUMAN |
| Immunogen Region | Ready-To-Use |
| Sample Type | serum, plasma, tissue homogenates or other biological fluids. |
Additional Info
| Tissue Specificity | |
| Post Translational Modifications | The enzyme can be inactivated by further oxidation of the cysteine sulfenic acid (C(P)-SOH) to sulphinic acid (C(P)-SO2H) instead of its condensation to a disulfide bond. It can be reactivated by forming a transient disulfide bond with sulfiredoxin SRXN1, which reduces the cysteine sulfinic acid in an ATP- and Mg-dependent manner. Acetylation increases resistance to transition to high molecular-mass complexes. Deacetylated by HDAC6 which decreases reducing activity. |
| Function | Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides and as sensor of hydrogen peroxide-mediated signaling events. Might participate in the signaling cascades of growth factors and tumor necrosis factor-alpha by regulating the intracellular concentrations of H(2)O(2). |
| Protein Name | Peroxiredoxin-2Natural Killer Cell-Enhancing Factor BNkef-BPrpThiol-Specific Antioxidant ProteinTsaThioredoxin Peroxidase 1Thioredoxin-Dependent Peroxide Reductase 1Thioredoxin-Dependent Peroxiredoxin 2 |
| Database Links | Reactome: R-HSA-3299685Reactome: R-HSA-5628897Reactome: R-HSA-8862803 |
| Cellular Localisation | Cytoplasm |
| Alternative ELISA Names | Peroxiredoxin-2 ELISA kitNatural Killer Cell-Enhancing Factor B ELISA kitNkef-B ELISA kitPrp ELISA kitThiol-Specific Antioxidant Protein ELISA kitTsa ELISA kitThioredoxin Peroxidase 1 ELISA kitThioredoxin-Dependent Peroxide Reductase 1 ELISA kitThioredoxin-Dependent Peroxiredoxin 2 ELISA kitPRDX2 ELISA kitNKEFB ELISA kitTDPX1 ELISA kit |
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Information sourced from Uniprot.org