Human PPP2R4 (Protein Phosphatase 2A Activator, Regulatory Subunit 4) Sandwich ELISA Kit (STJE0011625)

Human PPP2R4 (Protein Phosphatase 2A Activator, Regulatory Subunit 4) Sandwich ELISA Kit (STJE0011625)

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STJE0011625
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Short Description :This PPP2R4 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human tissue homogenates or other biological fluids..
Applications:ELISA
Reactivity:Human
Sensitivity:0.070ng/mL
Detection Limit:0.156-10ng/mL
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Storage Instruction:Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time:4.5 hrs
Gene Symbol:PTPA
Gene ID:5524
Uniprot ID:PTPA_HUMAN
Sample Type:tissue homogenates or other biological fluids.
Tissue Specificity Widely expressed.
Post Translational Modifications
Function PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. Acts as a regulatory subunit for serine/threonine-protein phosphatase 2A (PP2A). Modulates PP2A activity or substrate specificity, probably by inducing a conformational change in the catalytic subunit, a proposed direct target of the PPIase. Can reactivate inactive phosphatase PP2A-phosphatase methylesterase complexes (PP2A(i)) in presence of ATP and Mg(2+). Reversibly stimulates the variable phosphotyrosyl phosphatase activity of PP2A core heterodimer PP2A(D) in presence of ATP and Mg(2+) (in vitro). The phosphotyrosyl phosphatase activity is dependent of an ATPase activity of the PP2A(D):PPP2R4 complex. Is involved in apoptosis.the function appears to be independent from PP2A.
Protein Name Serine/Threonine-Protein Phosphatase 2a Activator
Pp2a - Subunit B' - Pr53 Isoform
Phosphotyrosyl Phosphatase Activator
Ptpa
Serine/Threonine-Protein Phosphatase 2a Regulatory Subunit 4
Serine/Threonine-Protein Phosphatase 2a Regulatory Subunit B'
Database Links
Cellular Localisation Cytoplasm
Nucleus
Alternative ELISA Names Serine/Threonine-Protein Phosphatase 2a Activator ELISA kit
Pp2a - Subunit B' - Pr53 Isoform ELISA kit
Phosphotyrosyl Phosphatase Activator ELISA kit
Ptpa ELISA kit
Serine/Threonine-Protein Phosphatase 2a Regulatory Subunit 4 ELISA kit
Serine/Threonine-Protein Phosphatase 2a Regulatory Subunit B' ELISA kit
PTPA ELISA kit
PPP2R4 ELISA kit
output

Information sourced from Uniprot.org

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