Human PPP1R13L protein (Recombinant) (N-His) (STJP007874)
SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human PPP1R13L-N-His protein was developed from e.coli for the region N-His. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
Target Information
| Gene Symbol | PPP1R13L |
| Gene ID | 10848 |
| Uniprot ID | IASPP_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Asn626-Gly816 |
Additional Info
| Function | Regulator that plays a central role in regulation of apoptosis and transcription via its interaction with NF-kappa-B and p53/TP53 proteins. Blocks transcription of HIV-1 virus by inhibiting the action of both NF-kappa-B and SP1. Also inhibits p53/TP53 function, possibly by preventing the association between p53/TP53 and ASPP1 or ASPP2, and therefore suppressing the subsequent activation of apoptosis. Is involved in NF-kappa-B dependent negative regulation of inflammatory response. |
| Protein Name | Rela-Associated InhibitorInhibitor Of Aspp ProteinProtein IasppNfkb-Interacting Protein 1Ppp1r13b-Like Protein |
| Database Links | Reactome: R-HSA-6804759 |
| Cellular Localisation | CytoplasmNucleusPredominantly Cytoplasmic But Also Nuclear |
| Alternative Protein Names | Rela-Associated Inhibitor proteinInhibitor Of Aspp Protein proteinProtein Iaspp proteinNfkb-Interacting Protein 1 proteinPpp1r13b-Like Protein proteinPPP1R13L proteinIASPP proteinNKIP1 proteinPPP1R13BL proteinRAI protein |
Information sourced from Uniprot.org