Human PPCS protein (Recombinant) (His-Tag) (STJP017199)
SPECIFICATIONS
HostE.coli
ImmunogenHuman
General Information
| Short Description | Recombinant-Human PPCS-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Applications | SDS-PAGE |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Concentration | 1 mg/mL |
| Formulation | Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 10% Glycerol |
| Storage Instruction | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | PPCS |
| Gene ID | 79717 |
| Uniprot ID | PPCS_HUMAN |
| Accession Number | NP_078940 |
| Immunogen | Human |
| Immunogen Region | 1-311aa |
| Immunogen Sequence | MGSSHHHHHH SSGLVPRGSH MAEMDPVAEF PQPPGAARWA EVMARFAARL GAQGRRVVLV TSGGTKVPLE ARPVRFLDNF SSGRRGATSA EAFLAAGYGV LFLYRARSAF PYAHRFPPQT WLSALRPSGP ALSGLLSLEA EENALPGFAE ALRSYQEAAA AGTFLAVEFT TLADYLHLLQ AAAQALNPLG PSAMFYLAAA VSDFYVPVSE MPEHKIQSSG GPLQITMK |
Additional Info
| Function | Catalyzes the second step in the biosynthesis of coenzyme A from vitamin B5, where cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. Has a preference for ATP over CTP as a cosubstrate. |
| Protein Name | Phosphopantothenate--Cysteine LigasePhosphopantothenoylcysteine SynthetasePpc Synthetase |
| Database Links | Reactome: R-HSA-196783 |
| Cellular Localisation | |
| Alternative Protein Names | Phosphopantothenate--Cysteine Ligase proteinPhosphopantothenoylcysteine Synthetase proteinPpc Synthetase proteinPPCS proteinCOAB protein |
Information sourced from Uniprot.org