Human POU2F2 protein (Recombinant) (N-His) (STJP003880)
SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human POU2F2-N-His protein was developed from e.coli for the region N-His. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
Target Information
| Gene Symbol | POU2F2 |
| Gene ID | 5452 |
| Uniprot ID | PO2F2_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Phe236-Thr398 |
Additional Info
| Function | Transcription factor that specifically binds to the octamer motif (5'-ATTTGCAT-3'). Regulates IL6 expression in B cells with POU2AF1. Regulates transcription in a number of tissues in addition to activating immunoglobulin gene expression. Modulates transcription transactivation by NR3C1, AR and PGR. Isoform 5: Activates the U2 small nuclear RNA (snRNA) promoter. |
| Protein Name | Pou Domain - Class 2 - Transcription Factor 2Lymphoid-Restricted Immunoglobulin Octamer-Binding Protein Nf-A2Octamer-Binding Protein 2Oct-2Octamer-Binding Transcription Factor 2Otf-2 |
| Database Links | Reactome: R-HSA-6807505 |
| Cellular Localisation | CytoplasmNucleus |
| Alternative Protein Names | Pou Domain - Class 2 - Transcription Factor 2 proteinLymphoid-Restricted Immunoglobulin Octamer-Binding Protein Nf-A2 proteinOctamer-Binding Protein 2 proteinOct-2 proteinOctamer-Binding Transcription Factor 2 proteinOtf-2 proteinPOU2F2 proteinOCT2 proteinOTF2 protein |
Information sourced from Uniprot.org